Betamethasone enemata in ulcerative colitis.
نویسنده
چکیده
In this series a very large therapeutic dose of corticosteroid was administered by retention enemata. For the first week the author gave the equivalent of between 300 and 750 mg. of cortisone daily and for the next three weeks 150 to 375 mg. daily. The results were excellent but systemic effects were noted in all who received more than the smallest dose used.
منابع مشابه
Urinary Excretion of Prednisolone after Intrarectal Therapy in Ulcerative Colitis.
Treatment of ulcerative colitis with betamethasone phosphate enemas was found to cause suppression of the adrenal cortex, so that absorption of betamethasone from the rectum can be inferred; no suppression occurred in similar patients treated with prednisolone phosphate enemas (Matts, Wharton, Kelleher, and Walters, 1963). In order to determine whether any rectal absorption of prednisolone does...
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In 1956, Truelove introduced the successful topical corticosteroid treatment for ulcerative colitis, using a modified blood transfusion set. To simplify the technique Matts (1960) introduced disposable plastic enema bags. We have extensively used both these methods. The modified blood transfusion set is better suited to inpatient than to out-patient treatment. The disposable bags, while simpler...
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ورودعنوان ژورنال:
- Gut
دوره 3 شماره
صفحات -
تاریخ انتشار 1962